I am honored to introduce a new Person of LWON, Laura Helmuth, who probably doesn’t need introducing at all, given that she has done everything (editing mostly, but also editing-in-chief and giving encouraging talks and getting a PhD in cognitive neuroscience and winning awards and being on every science writing committee and institution known to humankind) and has been everywhere (Science, Smithsonian, National Geographic, Slate, Washington Post, and Scientific American, that is, a good fraction of the science-related publications known to humankind). She now writes a spritely advice column for Slate for people trying to navigate their workplaces. She remains…

In biology, enzymes have evolved over millions of years to drive chemical reactions. Scientists from the Max Planck Institute for Dynamics and Self-Organization (MPI-DS) now derived universal rules to enable the de novo design of optimal enzymes. As an example, they considered the enzymatic reaction of breaking a dimer into two monomer molecules. Considering the geometry of such an enzyme-substrate-complex, they identified three golden rules that should be considered to build a functional enzyme. First, the interface of both enzyme and molecule should be located at their respective smaller end. This way, a strong coupling between both of them can…

Open science essentials in 2 minutes, part 4 Before a research article is published in a journal you can make it freely available for anyone to read. You could do this on your own website, but you can also do it on a preprint server, such as psyarxiv.com, where other researchers also share their preprints, which is supported by the OSF so will be around for a while, and which allows you to find others’ research easily. Preprint servers have been used for decades in physics, but are now becoming more common across academia. Preprints allow rapid dissemination of your…